In today's competitive nutrition Marketplace, products must have research that is documented for bioavailability and functionality. Think again, if you think all supplemental minerals are basically the same.

For example:

Which Iron nutrient is not only significantly more bioavailable (2 to 4 times) than ferrous salts, but is also tolerated much better?

• Which non-fat calcium source is more bioavailable than milk and twice as bioavailable as the carbonate source?
• Which form of magnesium is highly bioavailable and retained with no adverse effects on the bowel?
• Which zinc nutrient is more bioavailable than sulfates and picolinates?
• Which manganese is more bioavailable and yeast free?
• Which chromium has greater bioavailability than chromium salts?
• Which copper has higher bioavailability and is safer than copper salts?

The answers are all the same. Life Zone’s Amino Key Mineral Chelates!

Independent studies at major Universities show that these forms of Amino Acid Mineral Chelates have:

• Superior bioavailability
• Superior tolerance
• Higher nutrient density

When compared to other commercially available minerals.

In human nutrition, these patented mineral amino acid chelated minerals enhance the nutrient density of foods. In choosing a mineral supplement, the form of the mineral is crucial. It is the key factor that determines how well the body utilizes the mineral for bioavailability. One form of mineral may go into the body’s tissues while another form may wind up going down the toilet.

Man Made supplements however, typically use mineral salts such as carbonates, sulfates, and oxides, because of their low cost and mineral content. These salts can be found in nature, but

usually in the form of shells, bones, structural materials, or rocks. When was the last time you wanted to eat a rock, a bone, or an oyster’s shell to get your minerals?

The body has to modify these forms of mineral salts to assimilate the mineral. Mineral salts, (carbonates, sulfates, oxides etc.) must undergo complex digestive and transport processes. Patented mineral amino acid chelates are assimilated intact for total bioavailability and are ready for the body to identify and use. The amino acids are then metabolized and the mineral is released in the blood to do its work. There are 130 Patents from verified research, stability testing, bioavailability, safety, nutrient density, and better tolerated over other mineral salts as proven in University studies.

Sophisticated analytical testing has validated the patented mineral amino acid chelated minerals form a true nutritional chelate! These same tests have also shown that many other so called chelated are actually simple mixtures of an unreacted mineral salt and protein. Chelation of admixtures does not occur in the GI tract. Thus, imitation chelates are ineffective and mislabeled.

An article published in the medical journal Calcified Tissue International compared various food and supplemental calcium sources. The results showed that the patented amino acid mineral chelated used by Life Zone was superior to all other forms of calcium supplementation including milk. Carbonate and citrate calcium forms had roughly half the bioavailability of the calcium chelate that is used in Life Zone’s formulas.

Magnesium is a vital needed mineral in over 300 of the body’s enzymes including the bioenergetic processes. The majority of magnesium research has focused on cardiovascular health. New medical research shows magnesium also plays a healthy supporting role in bone, stress, exercise, migraines, depression, PMS and chronic fatigue. The average diet supplies only 15%-30% of the RDA of magnesium. However, 75% of the population ingest less than the RDA of magnesium. Standard blood tests do not accurately assess magnesium status, so many people falsely believe they have sufficient levels of magnesium. The patented amino acid magnesium mineral chelate used by Life Zone in a major medical school study showed that the intestinal uptake was 94 parts per million (ppm), compared to 77 (ppm) carbonate, 36 (ppm) sulfates, and 23 (ppm) on oxides.

Iron deficiency is the most common single nutrient deficiency in the world. 58% of the US population ingest less than the RDA for iron. It is even worse in developing countries. The average adult loses 1 mg. of iron per day. Exercisers lose about 1 mg. of sweat per workout. Menstruating women have an even greater demand on iron. Pregnant women require a minimum of 800 mg. Of iron during pregnancy. Iron is essential for growing children in relatively high amounts, for physical development, and also cognitive proficiency. Dr. O. Pineda at the Institute of Nutrition for Central America and Panama showed that taking 30 mg. patented amino acid mineral chelated iron raised hemoglobin levels faster and without the typical gastric stomach distress, constipation, bloating, diarrhea, and discomfort compared to taking 120 mg. Iron as Ferrous Sulfate that many individuals experience from taking a Ferrous Sulfate form of iron. Dr. Pieda also reported that the patented amino acid iron chelate was 4 times more bioavailable than the ferrous sulfate iron as published in the Journal of Applied Nutrition volume 46, Numbers 1 & 2. Life Zone uses this patented iron amino acid mineral chelate in its formulas.

Surveys indicate that 68% of the US population consume less than the RDA of zinc. Zinc plays

a crucial role in the synthesis of protein, DNA and RNA. It is a critical factor in activating the immune hormone Thymulin. Other functions of zinc relate to antioxidants, vision, taste, smell, growth, vitamin A metabolism and Immunity. Over 80 enzymes and hormones require zinc for optimal function as an amino acid mineral chelate. This is the form that Life Zone uses in its formulations.

Copper performs critical function in numerous enzymes too. It is a major in its catalytic role in the antioxidant superoxide dismutase (SOD) and ceruloplasmin. It is needed for the synthesis of hemoglobin, connective tissue, bone, thyroid hormones, and the catecholamines (epinephrine and dopamine). Research at Perdu University showed that patented amino acid copper mineral chelate increased red cell SOD levels by an average 28% in 21 rheumatoid arthritis. Life Zone uses this form of copper in its formulations.

Chromium is an ultra trace mineral involved in metabolism of glucose. Recent studies show an association between a chromium deficiency and elevated cholesterol. The research shows a higher bioavailability in patented amino acid chromium chelate chelate than from using chromium salts. This is why Life Zone uses the patented form of Chromium in its formulas versus the typical chromium salts and picolinates.

Selenium is a highly bioavailable patented amino acid mineral complex that is yeast free. Its major function is that of an antioxidant in the enzyme glutathione peroxidase. In this regard, selenium appears to be as much as 100 times more potent than vitamin E. If this mineral has low levels within the body there is an increased need for vitamin E. Selenium helps prevent degenerative changes in the pancreas. It also provides healthy support against mercury and cadmium poisoning, oxidative reactions, cardiovascular disease and premature aging. This patented form of amino acid selenium mineral complex is in Life Zone’s formulas.

Life Zone follows and uses validated scientific research that is time proven and tested combined with the wisdom of Nature in all of its natural, organic formulas. Safety, stability, and bioavailability that have stood the test of time.

REFERENCES

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Ashmead HD, Graff DJ, Ashmead HH: Intestinal Absorption of Metal Ions and chelates. Charles C. Thomas, Springfield, Illinois, 1985

Christensen JM: Effects of Divalent Amino Acids on Iron Absorption. J Pharm Sci. 1984; 73 (9) 12245-7.

DiSilvestro R. Effects of Copper Amino Acid Chelates on SOE levels in Rheumatoid Arthritis. In Press 1991.

Fairweather-Tate Sj. et al.: Iron and Zinc Bioavailability From Glycine Mineral Chelates. In Press 1991.

Heaney RP, Recker RR, Weaver CP: Absorbability of calcium sources: The limited Role of Solubility. Calcif Tissue int 1990; 46:300-304

Heaney RP: Absorbability of Calcium from Amino Acid Chelated Calcium. Unpublished Paper 1989.

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Pineda O: Comparison of An Iron Amino Acid Chelate versus Ferrous Sulfate in Anemic Children. Unpublished Research 1991. (INCAP).

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Schuette S. Tolerance of an Iron Chelate vs. Ferrous Sulfate in Normal Women. In Press.

Seals CJ and Wheaton FW. Chemical factors effecting the intestinal absorption of Zinc in vitro and invivo. Brit J Nutr 1983; 50:317-21.

Subramanina KS, Lyengar GV, Okamoto K: Biological Trace Element Research. American Chemical Society, Washington D.C. 1991.

Wapnir RA: Absorption of Zinc by the Rat LLeu: Effects of Histidine and osOther Low Molecular Weight Ligands. J Nutr 1983; 113:1346-54.

Weaver K, Spiegel KM: Platelet Functional Response to Oral Magnesium and Fish Oil in Human Volunteers. J AM Col Nut 1988; 7:407

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